| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Away | Footscray Bulldogs | 3.4 22 | 22.16 148 | -126 | Whitten Oval | 22/03/2025 | Match stats |
| R2 | Away | Geelong VFL | 9.6 60 | 13.12 90 | -30 | Kardinia Park | 29/03/2025 | Match stats |
| R3 | Away | Gold Coast Suns | 5.9 39 | 25.14 164 | -125 | Carrara Stadium | 05/04/2025 | Match stats |
| R5 | Away | Frankston Dolphins | 8.7 55 | 14.15 99 | -44 | Frankston Park | 24/04/2025 | Match stats |
| R6 | Home | Port Melbourne | 8.8 56 | 23.17 155 | -99 | Preston City Oval | 03/05/2025 | Match stats |
| R7 | Home | Collingwood VFL | 12.4 76 | 23.13 151 | -75 | Preston City Oval | 10/05/2025 | Match stats |
| R8 | Away | Coburg Lions | 10.9 69 | 15.9 99 | -30 | Coburg City Oval | 18/05/2025 | Match stats |
| R9 | Home | Casey Demons | 7.8 50 | 17.19 121 | -71 | Preston City Oval | 24/05/2025 | Match stats |
| R10 | Home | Southport | 10.7 67 | 27.14 176 | -109 | Preston City Oval | 31/05/2025 | Match stats |
| R11 | Away | GWS Giants | 7.5 47 | 23.12 150 | -103 | Blacktown Sportspark | 07/06/2025 | Match stats |
| R12 | Home | Carlton | 4.12 36 | 18.14 122 | -86 | Preston City Oval | 15/06/2025 | Match stats |
| R14 | Home | Richmond VFL | 5.8 38 | 14.12 96 | -58 | Preston City Oval | 28/06/2025 | Match stats |
| R15 | Away | Sydney Swans | Lakeside Oval | 05/07/2025 | ||||
| R16 | Home | Williamstown | Preston City Oval | 13/07/2025 | ||||
| R17 | Home | Frankston Dolphins | Preston City Oval | 20/07/2025 | ||||
| R18 | Home | Coburg Lions | Preston City Oval | 27/07/2025 | ||||
| R19 | Away | Port Melbourne | North Port Oval | 02/08/2025 | ||||
| R21 | Home | Werribee Tigers | Preston City Oval | 16/08/2025 |