| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Home | Box Hill Hawks | 12.4 76 | 11.14 80 | -4 | Princes Park | 21/03/2025 | Match stats |
| R3 | Home | Southport | Princes Park | 05/04/2025 | ||||
| R4 | Away | North Melbourne VFL | Arden St | 18/04/2025 | ||||
| R5 | Home | Geelong VFL | Princes Park | 27/04/2025 | ||||
| R6 | Away | Coburg Lions | Coburg City Oval | 04/05/2025 | ||||
| R7 | Home | Sandringham Zebras | Princes Park | 10/05/2025 | ||||
| R8 | Away | Sydney Swans | SCG | 16/05/2025 | ||||
| R9 | Home | Williamstown | Princes Park | 24/05/2025 | ||||
| R11 | Away | Essendon VFL | Windy Hill | 08/06/2025 | ||||
| R12 | Away | Northern Bullants | Preston City Oval | 15/06/2025 | ||||
| R13 | Home | North Melbourne VFL | Princes Park | 21/06/2025 | ||||
| R14 | Away | Port Melbourne | 28/06/2025 | |||||
| R15 | Away | Collingwood VFL | 05/07/2025 | |||||
| R16 | Home | Brisbane Lions | 12/07/2025 | |||||
| R17 | Away | Casey Demons | 19/07/2025 | |||||
| R19 | Away | Frankston Dolphins | 02/08/2025 | |||||
| R20 | Home | Gold Coast Suns | 09/08/2025 | |||||
| R21 | Away | Footscray Bulldogs | 16/08/2025 |